If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
Make sure your doctor knows if you are pregnant, may be pregnant, or planning to become pregnant.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
If you think that this medicine is not working as well after you have been taking it for a few weeks, do not increase the dose. Instead, check with your doctor.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
Appropriate studies have not been performed on the relationship of age to the effects of Rybix ODT, Ryzolt, and Ultram tablets in children younger than 16 years of age. Safety and efficacy have not been established.
Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. This medicine may cause some people to become drowsy, dizzy, lightheaded, or less alert than they are normally.
If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases.
Appropriate studies have not been performed on the relationship of age to the effects of Ultram ER extended-release tablets in the pediatric population. Safety and efficacy have not been established.
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Portions of this document last updated: March 01, 2017 Original article: /drugs-supplements/tramadol-oral-route/side-effects/drg.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
This may help prevent a possible worsening of your condition and reduce the possibility of withdrawal symptoms such as anxiety, diarrhea, headache, nausea, shivering, sweating, tremors, or trouble with sleeping. Do not stop suddenly taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it compley.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Getting up slowly may help lessen this problem. Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position.
Place the tablet in your mouth. It should melt quickly. Do not push the tablet through the foil. If you are using the disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not break, crush, or chew it. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. After the tablet has melted, swallow or take a sip of water.
Do not drink alcoholic beverages, and check with your doctor or dentist before taking any of these medicines while you are using this medicine. This medicine will add to the effects of alcohol and other CNS depressants (medicine that makes you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics.
Physical dependence may lead to side effects when you stop taking the medicine. When tramadol is used for a long time, it may become habit-forming (causing mental or physical dependence). It acts in the central nervous system (CNS) to relieve pain. Tramadol belongs to the group of medicines called opioid analgesics.
For non-prescription products, read the label or package ingredients carefully. l your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also l your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.
If you think you or someone else may have taken an overdose of tramadol, get emergency help at once. Signs of an overdose include convulsions (seizures); difficult or troubled breathing; irregular, fast or slow, or shallow breathing; pale or blue lips, fingernails, or skin; pinpoint pupils of the eyes, or shortness of breath.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. The amount of medicine that you take depends on the strength of the medicine.
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tramadol in the elderly. However, elderly patients are more likely to have unwanted side effects (e.g., constipation; lightheadedness, dizziness, or fainting; stomach upset; weakness) and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving tramadol.
Taking tramadol together with medicines that are used during surgery or dental or emergency treatments may cause increased side effects. Before having any kind of surgery (including dental surgery) or emergency treatment, l the doctor or dentist in charge that you are taking this medicine.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
Check with your doctor immediay if any of the following side effects occur:
Make sure your doctor knows about all the other medicines you are using. This medicine may increase your risk for seizures. (convulsions) and may cause a serious condition called serotonin syndrome.
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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Get emergency help immediay if any of the following symptoms of overdose occur:
Keep out of the reach of children.
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.
This medicine is available only with your doctor's prescription.
However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss a dose of this medicine, take it as soon as possible.
The presence of other medical problems may affect the use of this medicine. Make sure you l your doctor if you have any other medical problems, especially:.
Do not keep outdated medicine or medicine no longer needed.
This product is available in the following dosage forms:
Swallow the extended-release tablets whole with liquids. Do not break, crush, or chew it.
After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediay if you notice the following side effects:.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor ls you to do so.
Lying down for a while may also help relieve some other side effects, such as dizziness or lightheadedness that may occur. However, if nausea or vomiting continues, check with your doctor. Nausea or vomiting may occur, especially after the first couple of doses. This effect may go away if you lie down for awhile.
l your doctor if you have any sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let your doctor know if you or anyone in your family has bipolar disorder (manic-depressive disorder) or has tried to commit suicide. Report any unusual thoughts or behaviors that trouble you, especially if they are new or get worse quickly. This medicine can increase thoughts of suicide. Make sure your caregiver knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. l your doctor right away if you start to feel more depressed or have thoughts about hurting yourself.
Anaphylaxis can be life-threatening and requires immediate medical attention. This medicine may cause serious allergic reactions, including anaphylaxis. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; swelling of your hands, face, or mouth; or chest pain while you are using this medicine.
Tramadol is used to relieve moderate to moderay severe pain, including pain after surgery. The extended-release or long-acting tablets are used for chronic ongoing pain.
This is a decision you and your doctor will make. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. For this medicine, the following should be considered:.
Some side effects may occur that usually do not need medical attention. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Also, your health care professional may be able to l you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine.
It is very important that your doctor check your progress at regular visits to make sure the medicine is working properly and to check for any unwanted effects.
Drug information provided by: Micromedex.Tramadol and klonopin combination